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SARMs are experimental drugs that may or may not lead to suppressed natural testosterone production as these drugs are fairly new to the bodybuilding communityand thus have not been evaluated in the same way as older drugs such as testosterone enanthate. Testosterone is the primary hormone that contributes significantly to men's muscle mass and a large part of the strength of the muscle cells, which results in a higher protein metabolism with lower levels of catabolic enzymes, less fat storage and generally lower body fat. Because of the lower levels of growth hormone, and the less efficient use of fatty acid oxidation, men with excess testosterone can be more susceptible to heart disease than men without this testosterone deficiency. This in turn may be a contributor causing the higher risk of fatal coronary artery disease in men as well, a situation being made worse by the fact that high testosterone levels are known to promote the development of atherosclerosis. While it is well known that muscle growth is promoted by testosterone and is often associated with higher testosterone levels, more research is needed to determine whether high androgen exposure is an accurate predictor of muscle growth in men and what effects it may have on muscle growth. However due to the small population study (SARMs) conducted by the author of the article, the authors used the "best" method to measure their results, rather than using the same methods used by other research studies to test the association between testosterone and muscle growth. The authors of the study concluded without even testing the strength training program in men that their results would be inconclusive because both the "training variables" – i.e., strength training and endurance exercise – were not associated with testosterone at baseline or during the study. To summarize: 1) The author concludes that "excessive testosterone is associated with low muscle growth" but that the strength training alone resulted in a very small increase. 2) The results of the study are inconclusive because the strength training/ endurance training variable was not statistically associated with levels of testosterone, and the men did not get stronger while doing the exercise. 3) Testosterone is an indirect link with muscle growth, but that does not imply a direct relationship. 4) It is not known whether or not any type of testosterone administration would result in an increased muscle growth when done in conjunction with strength training in men. 5) It might be interesting to conduct a larger study involving multiple groups to see if there is an association. 6) It is important to point out that the article uses a "best" measurement method to measure testosterone levels; therefore the results of the study may be somewhat misleading. Similar articles:
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